Dr. Mario Rosemblatt.
Grado:
Ph.D. Wayne State University. USA, 1973.
Tema de investigación o interés:
Inmunología.
• Mecanismos de Regulación Inmune y Autoinmunidad.
Research Interest:
Immunology.
• Mechanisms of Immune Regulation and Autoimmunity.
Distinciones y premiaciones:
•Young Investigador Award NIH (1975)
•Chercher Invité, Association pour le Recherche sur le Cancer (ARC) Paris – France (1985)
•Premio al Mérito Universidad Andrés Bello, Mención Ciencias (2008)
•Premio a la Exelencia Académica (2008) Facultad de Ciencias, Universidad de Chile
Proyectos:
•“Modulación del homing en el sistema inmune”
FONDECYT
Investigador responsable: Prof. Mario Rosemblatt S.
Co-investigadora: Prof. María Rosa Bono M.
Duración: 2006 – 2010
•“Microambiente linfoide y polarización de la respuesta inmune”
FONDECYT
Investigadora responsable: Prof. María Rosa Bono M.
Co-investigador: Prof. Mario Rosemblatt S.
Duración: 2006 – 2010
•Proyecto Instituto Milenio de Biología Fundamental y Aplicada
Director Alterno
Duración 2006-2010
•Proyecto de Financiamiento Basal para Centros de Excelencia
Investigador Senior
Duración: 2008-2013
Publicaciones:
•Wilhelm V., Morales C., Martínez R., Rosemblatt M., Burzio L. O., Valenzuela P. D. T.
"Isolation and expression of the genes coding for the membrane bound transglycosidase B (MltB) and the transferring binding protein B (TbpB) of the salmon pathogen Piscirickettsia salmonis"
Biol. Res. 37: 783 - 793 (2005)
•Wilhelm V., Soza C., Martínez R., Rosemblatt M., Burzio L. O., Valenzuela P. D. T.
"Production and immune response of recombinant Hsp60 and Hsp70 from the salmon pathogen Piscirickettsia salmonis"
Biol. Res. 38: 69 - 82 (2005)
•Tischler N., Galeno H., Rosemblatt M., Valenzuela P. D. T.
"Human and rodent humoral immune response to Andes virus structural proteins"
Virology 334: 319 - 326 (2005)
•Naves R., Reyes L.I., Jacobelli S., González A., Rosemblatt M., Bono M.R.
“Lymphoid cells induce NF-KB activation in high endothelial cells from human tonsil”
International Immunology 18: 259 - 267 (2006)
•Vargas P., Cortés C., Vargas L., Rosemblatt M., Bono M.R.
“Immunization with antigen-pulsed dendritic cells significantly improves the immune response to weak self-antigens”
Immunobiology 211: 29 - 36 (2006)
•Wilhelm V., Miquel A., Burzio L. O., Rosemblatt M., Engel E., Valenzuela S., Parada G., Valenzuela P.
“A vaccine against the salmonid pathogen Piscirickettsia salmonis based on recombinant proteins”
Vaccine 24(23): 5083 - 5091 (2006)
•Bono M.R., R. Elgueta, D. Sauma, K. Pino, F. Osorio, P. Michea, A. Fierro and M. Rosemblatt.
“The essential role of chemokines in the selective regulation of lymphocyte homing”. Cytokine and growth Factor Reviews 18: 33-43 (2007).
•Ureta G., F. Osorio, J. Morales, M. Rosemblatt, M.R. Bono and J.A. Fierro.
“Generation of dendritic cells with regulatory properties”.
Transplantation Proceedings 39: 633-637 (2007).
•Micah J. Benson, Karina Pino-Lagos, Mario Rosemblatt and Randolph J. Noelle.
“All-trans retinoic acid mediates enhanced Treg growth, differentiation and gut homing in the face of high levels of co-stimulation”.
J. Exp. Med. 204: 1765-74 (2007)
•Elgueta R., F.E. Sepulveda, F. Vilches, L. Vargas, L.R. Mora, M.R. Bono and M. Rosemblatt.
“Imprinting of CCR9 on CD4 T cells requires IL-4 signalling on mesenteric lymph node dendritic cells”
In press, J. Immunol. 2008.
•Tischler, N. D. Rosemblatt, M. Valenzuela, P. D. Characterization of cross-reactive and serotype-specific epitopes on the nucleocapsid proteins of hantaviruses. Virus Research 135; 1-9 (2008).
•J. Morales, M.R. Bono, A. Fierro, R. Iñiguez, C. Zehnder, M. Rosemblatt, L. Calabran, C. Herzog, D. Benavente, J. Aguiló, J. Pefaur, A. Alba, M. Ferrario, W. Simon, L. Contreras, And E. Buckel. Alemtuzumab Induction in Kidney Transplantation: Clinical Results and Impact on T-Regulatory Cells. Transplat Proceedings 40; 3223-8 (2008)
•Gabrielle Faure-André, Pablo Vargas, Maria-Isabel Yuseff, Mélina Heuzé, Jheimmy Diaz, Danielle Lankar, Veronica Steri, Jeremy Manry, Stéphanie Hugues, Fulvia Vascotto, Jérôme Boulanger, Graça Raposo, Maria-Rosa Bono, Mario Rosemblatt, Matthieu Piel and Ana-Maria Lennon-Duménil. Regulation of Dendritic Cell Migration by CD74, the MHC Class II-Associated Invariant Chain. Science Dic 10 In Press (2008)